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Deriving the optimal limit of detection for an HCV point-of-care test for viraemic infection: Analysis of a global dataset.


BACKGROUND & AIMS: Affordable point-of-care tests for hepatitis C (HCV) viraemia are needed to improve access to treatment in low- and middle-income countries.

Auteurs: Freiman JM Wang J Easterbrook PJ Horsburgh CR Marinucci F White LF Kamkamidze G Krajden M Loarec A Njouom R Nguyen KV Shiha G Soliman R Solomon SS Tsertsvadze T Denkinger CM Linas B
Référence de l'article: Journal of hepatology 2019 Feb 21; (); Array. doi: 10.1016/j.jhep.2019.02.011. Epub 2019 02 21
Diagnosis Hepatitis C virus Limit of detection Point-of-care Viraemia, Affordable

Estimating cholera incidence with cross-sectional serology.


The development of new approaches to cholera control relies on an accurate understanding of cholera epidemiology.

Auteurs: Azman AS Lessler J Luquero FJ Bhuiyan TR Khan AI Chowdhury F Kabir A Gurwith M Weil AA Harris JB Calderwood SB Ryan ET Qadri F Leung DT
Référence de l'article: Science translational medicine 2019 Feb 20; 11(480); Array. doi: 10.1126/scitranslmed.aau6242. Epub 2019 03 29

Mortality in the first six months among HIV-positive and HIV-negative patients empirically treated for tuberculosis.


BACKGROUND: Empirical treatment of tuberculosis (TB) may be necessary in patients with negative or no Xpert MTB/RIF results.

Auteurs: Huerga H Ferlazzo G Wanjala S Bastard M Bevilacqua P Ardizzoni E Sitienei J Bonnet M
Référence de l'article: BMC infectious diseases 2019 Feb 11; 19(1); 132. doi: 10.1186/s12879-019-3775-z. Epub 2019 02 11
Diagnosis Empirical treatment HIV Mortality Resource-constrained Tuberculosis

Publisher Correction: Genomic insights into the 2016-2017 cholera epidemic in Yemen.


In the HTML version of this Letter, the affiliations for authors Andrew S. Azman, Dhirendra Kumar and Thandavarayan Ramamurthy were inverted (the PDF and print versions of the Letter were correct); the affiliations have been corrected online.

Auteurs: Weill FX Domman D Njamkepo E Almesbahi AA Naji M Nasher SS Rakesh A Assiri AM Sharma NC Kariuki S Pourshafie MR Rauzier J Abubakar A Carter JY Wamala JF Seguin C Bouchier C Malliavin T Bakhshi B Abulmaali HHN Kumar D Njoroge SM Malik MR Kiiru J Luquero FJ Azman AS Ramamurthy T Thomson NR Quilici ML
Référence de l'article: Nature 2019 02 ; 566(7745); E14. doi: 10.1038/s41586-019-0966-0. Epub 2019 03 08

Extremely low hepatitis C prevalence among HIV co-infected individuals in four countries in sub-Saharan Africa.


: A multicentric, retrospective case-series analysis (facility-based) in five sites across Kenya, Malawi, Mozambique, and Uganda screened HIV-positive adults for hepatitis C virus (HCV) antibodies using Oraquick rapid testing and viral confirmation (in

Auteurs: Loarec A Carnimeo V Molfino L Kizito W Muyindike W Andrieux-Meyer I Balkan S Nzomukunda Y Mwanga-Amumpaire J Ousley J Bygrave H Maman D
Référence de l'article: AIDS (London, England) 2019 Feb 01; 33(2); 353-355. doi: 10.1097/QAD.0000000000002070. Epub 2019 01 20

Demonstration of the diagnostic agreement of capillary and venous blood samples, using hepatitis-C virus SD Bioline rapid test: A clinic-based study.


BACKGROUND: Simplifying hepatitis C virus (HCV) screening is a key step in achieving the elimination of HCV as a global public health threat by 2030.

Auteurs: Sun C Iwamoto M Calzia A Sreng B Yann S Pin S Lastrucci C Kimchamroeun S Dimanche C Dousset JP Le Paih M Balkan S Marquardt T Carnimeo V Lissouba P Maman D Loarec A
Référence de l'article: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2019 Feb ; 111(); 39-41. doi: 10.1016/j.jcv.2018.12.008. Epub 2018 12 31
Blood specimen collection HCV screening Hepatitis C virus SD Bioline(©) Sample equivalence

Post-traumatic osteomyelitis in Middle East war-wounded civilians: resistance to first-line antibiotics in selected bacteria over the decade 2006-2016.


BACKGROUND: War-wounded civilians in Middle East countries are at risk of post-traumatic osteomyelitis (PTO).

Auteurs: Fily F Ronat JB Malou N Kanapathipillai R Seguin C Hussein N Fakhri RM Langendorf C
Référence de l'article: BMC infectious diseases 2019 Jan 31; 19(1); 103. doi: 10.1186/s12879-019-3741-9. Epub 2019 01 31
Bone biopsy First-line antibiotics resistance Middle East Osteomyelitis War-wounded

'I saw it as a second chance': A qualitative exploration of experiences of treatment failure and regimen change among people living with HIV on second- and third-line antiretroviral therapy in Kenya, Malawi and Mozambique.


Increasing numbers of people living with HIV (PLHIV) in sub-Saharan Africa are experiencing failure of first-line antiretroviral therapy and transitioning onto second-line regimens.

Auteurs: Burns R Borges J Blasco P Vandenbulcke A Mukui I Magalasi D Molfino L Manuel R Schramm B Wringe A
Référence de l'article: Global public health 2019 Jan 11; (); 1-13. doi: 10.1080/17441692.2018.1561921. Epub 2019 01 11
Antiretroviral therapy adherence second-line treatment sub-Saharan Africa treatment failure