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Plaidoyer contre l'exclusion des francophones dans la recherche en santé mondiale


La tenue de l'Africa Health Agenda International Conference (AHAIC) à Kigali (Rwanda) début mars 2019 a été l'occasion d'organiser un atelier de discussion en français qui a permis de recueillir les témoignages de participants francophones sur l'impact

Auteurs: Roca A Boum Y Wachsmuth I
Référence de l'article: The Lancet Global Health
Francophone Research Scientists Publishing Africa Health Agenda International Conference (AHAIC)

A screening tool for psychological difficulties in children aged 6 to 36 months: cross-cultural validation in Kenya, Cambodia and Uganda.


BACKGROUND: In low-resource settings, the lack of mental health professionals and cross-culturally validated screening instruments complicates mental health care delivery. This is especially the case for very young children.

Auteurs: Nackers F Roederer T Marquer C Ashaba S Maling S Mwanga-Amumpaire J Muny S Sokeo C Shom V Palha M Lefèbvre P Kirubi BW Kamidigo G Falissard B Moro MR Grais RF
Référence de l'article: BMC pediatrics 2019 Apr 12; 19(1); 108. doi: 10.1186/s12887-019-1461-3. Epub 2019 04 12
Cambodia Kenya Low-income population Mental health Preschool children Psychology Screening Uganda Validation

High incidence of intended partner pregnancy among men living with HIV in rural Uganda: Implications for safer conception services.


BACKGROUND: Many men with HIV express fertility intentions and nearly half have HIV-uninfected sexual partners. We measured partner pregnancy among a cohort of men accessing antiretroviral therapy (ART) in Uganda.

Auteurs: Kaida A Kabakyenga J Bwana M Bajunirwe F Muyindike W Bennett K Kembabazi A Haberer JE Boum Y Martin JN Hunt PW Bangsberg DR Matthews LT
Référence de l'article: Journal of acquired immune deficiency syndromes (1999) 2019 Apr 08; (); Array. doi: 10.1097/QAI.0000000000002053. Epub 2019 04 08

Diagnostic value of the urine lipoarabinomannan assay in HIV-positive, ambulatory patients with CD4 below 200 cells/μl in 2 low-resource settings: A prospective observational study.


BACKGROUND: Current guidelines recommend the use of the lateral flow urine lipoarabinomannan assay (LAM) in HIV-positive, ambulatory patients with signs and symptoms of tuberculosis (TB) only if they are seriously ill or have CD4 count

Auteurs: Huerga H Mathabire Rucker SC Cossa L Bastard M Amoros I Manhiça I Mbendera K Telnov A Szumilin E Sanchez-Padilla E Molfino L
Référence de l'article: PLoS medicine 2019 Apr ; 16(4); e1002792. doi: 10.1371/journal.pmed.1002792. Epub 2019 04 30

Risk score for predicting mortality including urine lipoarabinomannan detection in hospital inpatients with HIV-associated tuberculosis in sub-Saharan Africa: Derivation and external validation cohort study.


BACKGROUND: The prevalence of and mortality from HIV-associated tuberculosis (HIV/TB) in hospital inpatients in Africa remains unacceptably high.

Auteurs: Gupta-Wright A Corbett EL Wilson D van Oosterhout JJ Dheda K Huerga H Peter J Bonnet M Alufandika-Moyo M Grint D Lawn SD Fielding K
Référence de l'article: PLoS medicine 2019 Apr ; 16(4); e1002776. doi: 10.1371/journal.pmed.1002776. Epub 2019 04 05

Linear growth faltering and the role of weight attainment: Prospective analysis of young children recovering from severe wasting in Niger.


Efforts to reduce the impact of stunting have been largely independent of interventions to reduce the impact of wasting, despite the observation that the conditions can coexist in the same child and increase risk of death.

Auteurs: Isanaka S Hitchings MDT Berthé F Briend A Grais RF
Référence de l'article: Maternal & child nutrition 2019 Mar 23; (); e12817. doi: 10.1111/mcn.12817. Epub 2019 03 23
Niger child malnutrition linear growth stunting wasting weight gain

Further evidence of Mycobacterium tuberculosis in the sputum of culture-negative pulmonary tuberculosis suspects using an ultrasensitive molecular assay.


BACKGROUND: Rapid diagnosis of pulmonary tuberculosis (TB) is critical to TB control. However, many patients with paucibacillary TB disease remain undiagnosed. Current TB elimination goals require new tools to diagnose early disease.

Auteurs: Madico G Vinhas S Orr B White L Gaeddert M Miller NS Mpeirwe M Orikiriza P Mwanga-Amumpaire J Boum Y Palaci M Dietze R Jones-López EC
Référence de l'article: Tuberculosis (Edinburgh, Scotland) 2019 Mar 23; 116(); 1-7. doi: 10.1016/ Epub 2019 03 23
Culture-negative disease Diagnosis Genotyping Mycobacterium tuberculosis Paucibacillary disease

Treatment outcomes of patients switching from an injectable drug to bedaquiline during short standardized MDR-TB treatment in Mozambique.


Bedaquiline was recommended by WHO as the preferred option in treatment of MDR-TB patients with long regimen. However, no recommendation was given for the short MDR-TB regimen.

Auteurs: Bastard M Molfino L Mutaquiha C Galindo MA Zindoga P Vaz D Mahinça I du Cros P Rusch B Telnov A
Référence de l'article: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019 Mar 11; (); Array. doi: 10.1093/cid/ciz196. Epub 2019 03 11

Control of Ebola virus disease outbreaks: Comparison of health care worker-targeted and community vaccination strategies.


BACKGROUND: Health care workers (HCW) are at risk of infection during Ebola virus disease outbreaks and therefore may be targeted for vaccination before or during outbreaks.

Auteurs: Robert A Camacho A Edmunds WJ Baguelin M Muyembe Tamfum JJ Rosello A Kéïta S Eggo RM
Référence de l'article: Epidemics 2019 Mar 02; (); Array. doi: 10.1016/j.epidem.2019.03.001. Epub 2019 03 02
Ebola Health care workers Outbreak control Public health Vaccination