Publications

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Intravenous Rehydration for Severe Acute Malnutrition with Gastroenteritis.

Abstract

BACKGROUND: International recommendations advise against the use of intravenous rehydration therapy in children with severe acute malnutrition because of the concern about fluid overload, but evidence to support this concern is lacking

Maitland K Ouattara SM Sainna H Chara A Ogundipe OF Sunyoto T Hamaluba M Olupot-Olupot P Alaroker F Connon R Saidou Maguina A Okiror W Amorut D Mwajombo E Oguda E Mogaka C Langendorf C Dewez JE Ciglenecki I Gibb DM Coldiron ME Petrucci R George EC
The New England journal of medicine 2025 Jun 13; . doi: 10.1056/NEJMoa2505752. Epub 2025 06 13

Contribution of Maternal Adherence to the Effect of Multiple Micronutrient Supplementation During Pregnancy: A Systematic Review and Individual Participant Data Meta-analysis.

Abstract

Multiple micronutrient supplements (MMSs) in pregnancy reduces risk of infant low birthweight (LBW) and improves other maternal and infant outcomes compared with iron and folic acid (IFA) supplements alone.

Smith ER Gomes F Adu-Afarwuah S Aguayo VM El Arifeen S Bhutta ZA Caniglia EC Christian P Devakumar D Dewey KG Fawzi WW Friis H Gomo E Guindo O Hallamaa L Isanaka S Kæstel P Lachat C Maleta K Moore SE Oakley EM Osrin D Rahman A Rana Z Rizvi A Roberfroid D Shaikh S Sonko B Soofi SB Subarkah I Sunawang R Wang D West KP Wu LSF Zagre N Bourassa MW Sudfeld CR
Advances in nutrition (Bethesda, Md.) 2025 May 30; . doi: 10.1016/j.advnut.2025.100455. Epub 2025 05 30
antenatal care individual participant data meta-analysis multiple micronutrient supplements pregnancy

Sequelae following an epidemic of meningococcal meningitis in Niger in 2022.

Abstract

BACKGROUND: The management of post-meningitis sequelae is a priority in the WHO Roadmap to Defeat Meningitis by 2030.

Idrissa AA Atti S Wasaulua RK Kazadi S Sani O Tassiou EI Guindo O Tonamou G Ciglenecki I Coldiron ME
PloS one 2025 ; 20(5); . doi: 10.1371/journal.pone.0323223. Epub 2025 05 22

Burden of Malaria in Adults in Sahelian Niger: A Retrospective Study (2019-2021).

Abstract

In the Sahel, malaria transmission is highly dependent on rainfall, and control efforts are conducted during the rainy season.

Aminou EYYM Djedanem M Ramatoulaye L Al Moustapha W Hamidou Leyo I Testa J Jambou R
The American journal of tropical medicine and hygiene 2025 May 20; . doi: 10.4269/ajtmh.24-0613. Epub 2025 05 20

Effectiveness of a bedaquiline, linezolid, clofazimine 'core' for multidrug-resistant TB.

Abstract

BACKGROUND: Treatment outcomes may be compromised among individuals with multidrug/rifampicin-resistant TB (MDR/RR-TB) with fluoroquinolone (FQ) resistance.

Zeng C Hernán MA Trevisi L Sauer S Mitnick CD Hewison C Bastard M Khan P Seung KJ Rich ML Law S Kikvidze M Kirakosyan O Miankou A Thit P Mamsa S Janmohamed A Melikyan N Ahmed S Vargas D Binegdie AB Temirova K Oyewusi L Philippe K Vilbrun SC Khan U Huerga H Franke MF
IJTLD open 2025 May ; 2(5); . doi: 10.5588/ijtldopen.24.0515. Epub 2025 05 12
MDR-TB endTB observational study fluoroquinolone resistance inverse-probability weighting rifampicin resistance target trial tuberculosis

Using an analogue-digital hybrid clinical data management platform during a two-dose preventive Ebola virus vaccine trial in Goma, the Democratic Republic of the Congo.

Abstract

Clinical trials in settings with intermittent or non-existent internet and power connectivity, for example during humanitarian emergencies, present challenges in the synchronisation of data across different sites, in addition to accessing a centralised

Brindle HE Tetsa-Tata D Edwards T Choi EM Kasonia K Aboubacar S Mambula G Kavunga-Membo H Grais R Johnson J Bausch DG Muyembe-Tamfum JJ Ama IS Lees S Watson-Jones D Camacho A Roberts CH
PLOS global public health 2025 ; 5(5); . doi: 10.1371/journal.pgph.0004487. Epub 2025 05 02

Prevalence of hepatitis C virus seropositivity and active infection in a Rohingya refugee population in Cox's Bazar camps, Bangladesh: a cross-sectional study.

Abstract

BACKGROUND: Hepatitis C virus (HCV) infection is a significant public health concern. Limited data have shown unusually high HCV seroprevalence among Rohingya refugees residing in camps in Cox's Bazar, Bangladesh.

Schramm B Ashakin KA Firuz W Hadiuzzaman M Ben-Farhat J Arias-Rodríguez A Rahman A Gupta PS Bhuiyan ATRH Duka M Balkan S Hossain F
The lancet. Gastroenterology & hepatology 2025 Apr 30; . doi: 10.1016/S2468-1253(25)00094-9. Epub 2025 04 30

Fexinidazole as a new oral treatment for human African trypanosomiasis due to Trypanosoma brucei rhodesiense: a prospective, open-label, single-arm, phase 2-3, non-randomised study.

Abstract

BACKGROUND: Rhodesiense human African trypanosomiasis is a neglected disease with epidemic potential that can rapidly become lethal if left untreated.

Matovu E Nyirenda W Eriatu A Alves D Perdrieu C Lemerani M Wamboga C Lejon V Seixas J Signorell A Reymondier A Baudin E Scherrer B Valverde Mordt O
The Lancet. Global health 2025 May ; 13(5); . doi: 10.1016/S2214-109X(25)00016-6. Epub 2025 04 28

COVID-19, tuberculosis, and HIV triad: a prospective observational study in ambulatory patients in Kenya, Uganda, and South Africa.

Abstract

People living with HIV (PLHIV) have an increased risk of tuberculosis (TB) and severe COVID-19. TB and COVID-19 present with overlapping symptoms and co-infection can lead to poor outcomes.

Huerga H Gouillou M Ohler L Taremwa IM Akinyi M Lubega A Muyindike WR Bastard M Bossard C Atieno M Muhindo R Casas EC Nakiyingi L Casenghi M Gupta-Wright A Bonnet M Ndlovu Z
PLOS global public health 2025 ; 5(4); . doi: 10.1371/journal.pgph.0004471. Epub 2025 04 23

The aetiologies, mortality, and disability of non-traumatic coma in African children: a systematic review and meta-analysis.

Abstract

BACKGROUND: Non-traumatic coma in African children is a common life-threatening presentation often leading to hospital attendance.

Ray STJ Fuller CE Boubour A Tshimangani T Kafoteka E Muiruri-Liomba A Malenga A Tebulo A Pensulo P Gushu MB Nielsen M Raees M Stockdale E Langton J Birbeck GL Waithira N Bonnett LJ Henrion MY Fink EL Postels DG O'Brien N Page AL Baron E Gordon SB Molyneux E Dondorp A George EC Maitland K Michael BD Solomon T Chimalizeni Y Lalloo DG Moxon CA Taylor T Mallewa M Idro R Seydel K Griffiths MJ
The Lancet. Global health 2025 Apr 22; . doi: 10.1016/S2214-109X(25)00055-5. Epub 2025 04 22