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Burden and risk factors for relapse following successful treatment of uncomplicated severe acute malnutrition in young children: Secondary analysis from a randomised trial in Niger.


This study aimed to quantify the burden of relapse following successful treatment for uncomplicated severe acute malnutrition (SAM) and to identify associated risk factors in rural Niger.

Bliznashka L Grantz KH Botton J Berthé F Garba S Hanson KE Grais RF Isanaka S
Maternal & child nutrition 2022 Jul 21; . doi: 10.1111/mcn.13400. Epub 2022 07 21
Niger community-based management of acute malnutrition discharge hospitalisation relapse severe acute malnutrition wasting
Ratnayake R Peyraud N Ciglenecki I Gignoux E Lightowler M Azman AS Gakima P Ouamba JP Sagara JA Ndombe R Mimbu N Ascorra A Epicentre and MSF CATI Working Group Welo PO Mukamba Musenga E Miwanda B Boum Y Checchi F Edmunds WJ Luquero F Porten K Finger F
BMJ open 2022 07 06; 12(7); . doi: 10.1136/bmjopen-2022-061206. Epub 2022 07 06
epidemiology geographical mapping infection control public health

Gender equity in health research publishing in Africa.


INTRODUCTION: Women researchers find it more difficult to publish in academic journals than men, an inequity that affects women's careers and was exacerbated during the pandemic, particularly for women in low-income and middle-income c

Baobeid A Faghani-Hamadani T Sauer S Boum Y Hedt-Gauthier BL Neufeld N Odhiambo J Volmink J Shuchman M Di Ruggiero E Condo JU
BMJ global health 2022 Jul ; 7(7); . doi: 10.1136/bmjgh-2022-008821. Epub 2022 07 14
Public Health

Capacity Building in Sub-Saharan Africa as Part of the INTENSE-TBM Project During the COVID-19 Pandemic.


Tuberculous meningitis (TBM) is the most severe and disabling form of tuberculosis (TB), with at least 100,000 cases per year and a mortality rate of up to 50% in individuals co-infected with human immunodeficiency virus type 1 (HIV-1).

Ariza-Vioque E Ello F Andriamamonjisoa H Machault V González-Martín J Calvo-Cortés MC Eholié S Tchabert GA Ouassa T Raberahona M Rakotoarivelo R Razafindrakoto H Rahajamanana L Wilkinson RJ Davis A Maxebengula M Abrahams F Muzoora C Nakigozi N Nyehangane D Nanjebe D Mbega H Kaitano R Bonnet M Debeaudrap P Miró JM Anglaret X Rakotosamimanana N Calmy A Bonnet F Ambrosioni J
Infectious diseases and therapy 2022 Jun 29; . doi: 10.1007/s40121-022-00667-z. Epub 2022 06 29
Africa Capacity building Clinical research HIV INTENSE-TBM Tuberculous meningitis

Integrating hepatitis C treatment into multidrug-resistant TB care.


BACKGROUND: Direct-acting antivirals (DAAs) are not widely used for patients with chronic hepatitis C virus (HCV) infection and multidrug- or rifampicin-resistant TB (MDR/RR-TB).

Kirakosyan O Melikyan N Falcao J Khachatryan N Atshemyan H Oganezova I Aznauryan A Yeghiazaryan L Sargsyants N Hayrapetyan A Balkan S Hewison C Huerga H
Public health action 2022 Jun 21; 12(2); . doi: 10.5588/pha.22.0002. Epub 2022 06 23
DAAs HCV MDRTB direct-acting antivirals integrated care
Sadler K James PT Bhutta ZA Briend A Isanaka S Mertens A Myatt M O'Brien KS Webb P Khara T Wells JC
The Journal of nutrition 2022 Jun 10; . doi: 10.1093/jn/nxac091. Epub 2022 06 10
child nutrition concurrent wasting and stunting mortality risk research design stunting wasting

Effectiveness of typhoid conjugate vaccine in Zimbabwe used in response to an outbreak among children and young adults: A matched case control study.


BACKGROUND: Zimbabwe suffers from regular outbreaks of typhoid fever (TF), worse since 2017. Most cases were in Harare and a vaccination campaign with Typhoid Conjugate Vaccine (TCV) was conducted in March 2019.

Lightowler MS Manangazira P Nackers F Van Herp M Phiri I Kuwenyi K Panunzi I Garone D Marume F Tarupiwa A Ferreras E Duri C Luquero FJ
Vaccine 2022 Jun 08; . doi: 10.1016/j.vaccine.2022.04.093. Epub 2022 06 08
Conjugate Effectiveness Outbreak Typhoid fever Vaccine Zimbabwe

Cost-effectiveness of monthly follow-up for the treatment of uncomplicated severe acute malnutrition: An economic evaluation of a randomized controlled trial.


Severe acute malnutrition (SAM) is a major source of mortality for children in low resource settings. Alternative treatment models that improve acceptability and reduce caregiver burden are needed to improve treatment access.

Menzies NA Berthé F Hitchings M Aruna P Hamza MA Nanama S Steve-Edemba C Shehu I Grais RF Isanaka S
PLOS global public health 2022 ; 2(12); . doi: 10.1371/journal.pgph.0001189. Epub 2022 12 09

Diagnostic accuracy of WHO screening criteria to guide lateral-flow lipoarabinomannan testing among HIV-positive inpatients: A systematic review and individual participant data meta-analysis.


BACKGROUND: WHO recommends urine lateral-flow lipoarabinomannan (LF-LAM) testing with AlereLAM in HIV-positive inpatients only if screening criteria are met.

Dhana A Hamada Y Kengne AP Kerkhoff AD Broger T Denkinger CM Rangaka MX Gupta-Wright A Fielding K Wood R Huerga H Rücker SCM Bjerrum S Johansen IS Thit SS Kyi MM Hanson J Barr DA Meintjes G Maartens G
The Journal of infection 2022 May 16; . doi: 10.1016/j.jinf.2022.05.010. Epub 2022 05 16
Diagnosis Human immunodeficiency virus Inpatient LAM Lipoarabinomannan Screening Sensitivity Specificity Tuberculosis

Measuring the unknown: An estimator and simulation study for assessing case reporting during epidemics.


The fraction of cases reported, known as 'reporting', is a key performance indicator in an outbreak response, and an essential factor to consider when modelling epidemics and assessing their impact on populations.

Jarvis CI Gimma A Finger F Morris TP Thompson JA le Polain de Waroux O Edmunds WJ Funk S Jombart T
PLoS computational biology 2022 05 ; 18(5); . doi: 10.1371/journal.pcbi.1008800. Epub 2022 05 23