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Alternative observational designs to estimate the effectiveness of one dose of oral cholera vaccine in Lusaka, Zambia.


We conducted a matched case-control (MCC), test-negative case-control (TNCC) and case-cohort study in 2016 in Lusaka, Zambia, following a mass vaccination campaign. Confirmed cholera cases served as cases in all three study designs.

Auteurs: Ferreras E Blake A Chewe O Mwaba J Zulu G Poncin M Rakesh A Page AL Quilici ML Azman AS Cohuet S Ciglenecki I Malama K Chizema-Kawesha E Luquero FJ
Référence de l'article: Epidemiology and infection 2020 Mar 13; 148(); e78. doi: 10.1017/S095026882000062X. Epub 2020 03 13
Cholera infectious disease epidemiology public health vaccine policy development

Energy needs in the treatment of uncomplicated severe acute malnutrition: Secondary analysis to optimize delivery of ready-to-use therapeutic foods.


Outpatient therapeutic feeding protocols for the treatment of uncomplicated severe acute malnutrition in children were initially based on weight gain data from inpatient settings and expert knowledge of the physiological requirements during recovery.

Auteurs: Isanaka S Andersen CT Hanson KE Berthé F Grais RF Briend A
Référence de l'article: Maternal & child nutrition 2020 Mar 07; (); e12989. doi: 10.1111/mcn.12989. Epub 2020 03 07
Niger community-based management of acute malnutrition energy requirement ready-to-use therapeutic food severe acute malnutrition weight gain

Intrahousehold management and use of nutritional supplements during the hunger gap in Maradi region, Niger: a qualitative study.


Background: Nutritional supplements are used for preventing and treating childhood malnutrition.

Auteurs: Marquer C Langendorf C Woi-Messe LC Berthe F Ategbo EA Rodas-Moya S dePee S Grais RF
Référence de l'article: BMC nutrition 2020 ; 6(); 4. doi: 10.1186/s40795-019-0329-0. Epub 2020 03 03
Children Distribution Malnutrition Management Maradi Niger Perception Supplementary food

Increased risk of acquisition and transmission of ESBL-producing Enterobacteriaceae in malnourished children exposed to amoxicillin.


OBJECTIVES: Routine amoxicillin for children with uncomplicated severe acute malnutrition raises concerns of increasing antibiotic resistance.

Auteurs: Maataoui N Langendorf C Berthe F Bayjanov JR van Schaik W Isanaka S Grais RF Clermont O Andremont A Armand-Lefèvre L Woerther PL
Référence de l'article: The Journal of antimicrobial chemotherapy 2020 03 01; 75(3); 709-717. doi: 10.1093/jac/dkz487. Epub 2020 12 22

"We give them threatening advice…": expectations of adherence to antiretroviral therapy and their consequences among adolescents living with HIV in rural Malawi.


INTRODUCTION: Many adolescents living with HIV in sub-Saharan Africa struggle to achieve optimal adherence to antiretroviral therapy (ART), but few studies have investigated how their treatment-taking decisions are influenced by their

Auteurs: Burns R Magalasi D Blasco P Szumilin E Pasquier E Schramm B Wringe A
Référence de l'article: Journal of the International AIDS Society 2020 Mar ; 23(3); e25459. doi: 10.1002/jia2.25459. Epub 2020 03 20
Malawi adherence adolescents living with HIV antiretroviral therapy qualitative

Effects and cost of different strategies to eliminate hepatitis C virus transmission in Pakistan: a modelling analysis.


BACKGROUND: The WHO elimination strategy for hepatitis C virus advocates scaling up screening and treatment to reduce global hepatitis C incidence by 80% by 2030, but little is known about how this reduction could be achieved and the c

Auteurs: Lim AG Walker JG Mafirakureva N Khalid GG Qureshi H Mahmood H Trickey A Fraser H Aslam K Falq G Fortas C Zahid H Naveed A Auat R Saeed Q Davies CF Mukandavire C Glass N Maman D Martin NK Hickman M May MT Hamid S Loarec A Averhoff F Vickerman P
Référence de l'article: The Lancet. Global health 2020 Mar ; 8(3); e440-e450. doi: 10.1016/S2214-109X(20)30003-6. Epub 2020 02 24

The duration of chemoprophylaxis against malaria after treatment with artesunate-amodiaquine and artemether-lumefantrine and the effects of pfmdr1 86Y and pfcrt 76T: a meta-analysis of individual patient data.


BACKGROUND: The majority of Plasmodium falciparum malaria cases in Africa are treated with the artemisinin combination therapies artemether-lumefantrine (AL) and artesunate-amodiaquine (AS-AQ), with amodiaquine being also widely used a

Auteurs: Bretscher MT Dahal P Griffin J Stepniewska K Bassat Q Baudin E D'Alessandro U Djimde AA Dorsey G Espié E Fofana B González R Juma E Karema C Lasry E Lell B Lima N Menéndez C Mombo-Ngoma G Moreira C Nikiema F Ouédraogo JB Staedke SG Tinto H Valea I Yeka A Ghani AC Guerin PJ Okell LC
Référence de l'article: BMC medicine 2020 Feb 25; 18(1); 47. doi: 10.1186/s12916-020-1494-3. Epub 2020 02 25
Amodiaquine Artemisinin Crt Drug Lumefantrine Malaria Mathematical model Trial mdr1