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Field evaluation of GeneXpert (Cepheid) HCV performance for RNA quantification in a genotype 1 and 6 predominant patient population in Cambodia.


GeneXpert (Cepheid) is the only WHO prequalified platform for hepatitis C virus (HCV) nucleic acid amplification testing that is suitable for point-of-care use in resource-limited contexts.

Auteurs: Iwamoto M Calzia A Dublineau A Rouet F Nouhin J Yann S Pin S Sun C Sann K Dimanche C Lastrucci C Coulborn RM Maman D Dousset JP Loarec A
Référence de l'article: Journal of viral hepatitis 2019 Jan ; 26(1); 38-47. doi: 10.1111/jvh.13002. Epub 2018 12 03
Cambodia HCV genotype 6 Hepatitis C Point-of-care testing RNA viral load

Genomic insights into the 2016-2017 cholera epidemic in Yemen.


Yemen is currently experiencing, to our knowledge, the largest cholera epidemic in recent history. The first cases were declared in September 2016, and over 1.1 million cases and 2,300 deaths have since been reported.

Auteurs: Weill FX Domman D Njamkepo E Almesbahi AA Naji M Nasher SS Rakesh A Assiri AM Sharma NC Kariuki S Pourshafie MR Rauzier J Abubakar A Carter JY Wamala JF Seguin C Bouchier C Malliavin T Bakhshi B Abulmaali HHN Kumar D Njoroge SM Malik MR Kiiru J Luquero FJ Azman AS Ramamurthy T Thomson NR Quilici ML
Référence de l'article: Nature 2019 01 ; 565(7738); 230-233. doi: 10.1038/s41586-018-0818-3. Epub 2019 01 02

Dual screen and confirm rapid test does not reduce overtreatment of syphilis in pregnant women living in a non-venereal treponematoses endemic region: a field evaluation among antenatal care attendees in Burkina Faso.


OBJECTIVES: In resource-limited settings, screening pregnant women for syphilis using rapid diagnostic tests (RDTs) is a key tool in the prevention of congenital syphilis.

Auteurs: Langendorf C Lastrucci C Sanou-Bicaba I Blackburn K Koudika MH Crucitti T
Référence de l'article: Sexually transmitted infections 2018 Dec 22; (); Array. doi: 10.1136/sextrans-2018-053722. Epub 2018 12 22
Burkina Faso antenatal care diagnostic test pregnant women treponemal infections

High prevalence of infection and low incidence of disease in child contacts of patients with drug-resistant tuberculosis: a prospective cohort study.


OBJECTIVE: We aimed to measure the prevalence and incidence of latent tuberculosis infection (LTBI) and tuberculosis (TB) disease in children in close contact with patients with drug-resistant TB (DR-TB) in a country with high DR-TB pr

Auteurs: Huerga H Sanchez-Padilla E Melikyan N Atshemyan H Hayrapetyan A Ulumyan A Bastard M Khachatryan N Hewison C Varaine F Bonnet M
Référence de l'article: Archives of disease in childhood 2018 Dec 06; (); Array. doi: 10.1136/archdischild-2018-315411. Epub 2018 12 06
drug-resistance epidemiology infectious diseases screening tuberculosis
Auteurs: Camacho A Bouhenia M Azman AS Poncin M Zagaria N Luquero FJ
Référence de l'article: The Lancet. Global health 2018 Dec ; 6(12); e1284-e1285. doi: 10.1016/S2214-109X(18)30395-4. Epub 2018 10 10

Oral cholera vaccination in hard-to-reach communities, Lake Chilwa, Malawi.


Objective: To evaluate vaccination coverage, identify reasons for non-vaccination and assess satisfaction with two innovative strategies for distributing second doses in an oral cholera vaccine campaign in 2016 in Lake Chilwa, Malawi,

Auteurs: Grandesso F Rafael F Chipeta S Alley I Saussier C Nogareda F Burns M Lechevalier P Page AL Salumu L Pezzoli L Mwesawina M Cavailler P Mengel M Luquero FJ Cohuet S
Référence de l'article: Bulletin of the World Health Organization 2018 Dec 01; 96(12); 817-825. doi: 10.2471/BLT.17.206417. Epub 2018 09 27

Urban yellow fever outbreak-Democratic Republic of the Congo, 2016: Towards more rapid case detection.


BACKGROUND: Between December 2015 and July 2016, a yellow fever (YF) outbreak affected urban areas of Angola and the Democratic Republic of the Congo (DRC).

Auteurs: Ingelbeen B Weregemere NA Noel H Tshapenda GP Mossoko M Nsio J Ronsse A Ahuka-Mundeke S Cohuet S Kebela BI
Référence de l'article: PLoS neglected tropical diseases 2018 12 ; 12(12); e0007029. doi: 10.1371/journal.pntd.0007029. Epub 2018 12 07
Auteurs: Hewison C Bastard M Varaine F Huerga H
Référence de l'article: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2018 Dec 01; 22(12); 1524-1525. doi: 10.5588/ijtld.18.0472-2. Epub 2019 01 04

Prevalence and vaccination coverage of Hepatitis B among healthcare workers in Cameroon: A national seroprevalence survey.


Hepatitis B virus (HBV) infection is hyperendemic in Cameroon, and healthcare workers (HCWs) are at high risk of infection. We aimed to assess prevalence, risk factors and vaccine coverage of HBV infection among HCWs in Cameroon.

Auteurs: Bilounga Ndongo C Eteki L Siedner M Mbaye R Chen J Ntone R Donfack O Bongwong B Essaka Evoue R Zeh F Njouom R Nguefack-Tsague G Etoundi Mballa GA Biwole Sida M Boum Y
Référence de l'article: Journal of viral hepatitis 2018 Dec ; 25(12); 1582-1587. doi: 10.1111/jvh.12974. Epub 2018 08 28
Cameroon healthcare workers hepatitis B prevalence vaccine efficacy

Identifying human encounters that shape the transmission of Streptococcus pneumoniae and other acute respiratory infections.


Although patterns of social contacts are believed to be an important determinant of infectious disease transmission, it remains unclear how the frequency and nature of human interactions shape an individual's risk of infection.

Auteurs: le Polain de Waroux O Flasche S Kucharski AJ Langendorf C Ndazima D Mwanga-Amumpaire J Grais RF Cohuet S Edmunds WJ
Référence de l'article: Epidemics 2018 12 ; 25(); 72-79. doi: 10.1016/j.epidem.2018.05.008. Epub 2018 05 19
Contact Infection Pneumococcus Respiratory Risk factor Transmission Uganda