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High prevalence of NRTI and NNRTI drug resistance among ART-experienced, hospitalized inpatients.


BACKGROUND: Patients hospitalized with advanced HIV have a high mortality risk.

Auteurs: Bossard C Schramm B Wanjala S Jain L Mucinya G Opollo V Wiesner L Van Cutsem G Poulet E Szumilin E Ellman T Maman D
Référence de l'article: Journal of acquired immune deficiency syndromes (1999) 2021 Apr 01; (); Array. doi: 10.1097/QAI.0000000000002689. Epub 2021 04 01

Epidemiological, clinical, and public health response characteristics of a large outbreak of diphtheria among the Rohingya population in Cox's Bazar, Bangladesh, 2017 to 2019: A retrospective study.


BACKGROUND: Unrest in Myanmar in August 2017 resulted in the movement of over 700,000 Rohingya refugees to overcrowded camps in Cox's Bazar, Bangladesh. A large outbreak of diphtheria subsequently began in this population.

Auteurs: Polonsky JA Ivey M Mazhar KA Rahman Z le Polain de Waroux O Karo B Jalava K Vong S Baidjoe A Diaz J Finger F Habib ZH Halder CE Haskew C Kaiser L Khan AS Sangal L Shirin T Zaki QA Salam A White K
Référence de l'article: PLoS medicine 2021 Apr 01; 18(4); e1003587. doi: 10.1371/journal.pmed.1003587. Epub 2021 04 01

Performance and operational feasibility of antigen and antibody rapid diagnostic tests for COVID-19 in symptomatic and asymptomatic patients in Cameroon: a clinical, prospective, diagnostic accuracy study.


Background: Real-time PCR is recommended to detect SARS-CoV-2 infection. However, PCR availability is restricted in most countries.

Auteurs: Yap Boum Karl Njuwa Fai Birgit Nicolay Akenji Blaise Mboringong Lisa M Bebell Mark Ndifon et al.
Référence de l'article:
Covid-19 RDT Cameroon antigen antibody

Decentralised hepatitis C testing and treatment in rural Cambodia: evaluation of a simplified service model integrated in an existing public health system.


BACKGROUND: Direct-acting antiviral treatment for hepatitis C virus (HCV) has provided the opportunity for simplified models of care delivered in decentralised settings by non-specialist clinical personnel.

Auteurs: Meiwen Zhang Daniel O’Keefe Jennifer Craig Keo Samley Voeurng Bunreth Pascal Jolivet Suna Balkan Tonia Marquardt Jean-Philippe Dousset Mickael Le Paih
Référence de l'article: Lancet Gastroenterol Hepatol 2021 Published Online March 18, 2021.
Hépatite C Evaluation Cambodge

Hepatitis C viraemic and seroprevalence and risk factors for positivity in Northwest Cambodia: a household cross-sectional serosurvey.


BACKGROUND: Despite a dramatic reduction in HCV drug costs and simplified models of care, many countries lack important information on prevalence and risk factors to structure effective HCV services.

Auteurs: Lynch E Falq G Sun C Bunchhoeung PDT Huerga H Loarec A Dousset JP Marquardt T Paih ML Maman D
Référence de l'article: BMC infectious diseases 2021 Feb 26; 21(1); 223. doi: 10.1186/s12879-021-05826-0. Epub 2021 02 26
Cambodia HCV Hepatitis C MSF Sero-prevalence Serosurvey Viraemia

Surveillance of Plasmodium falciparum pfcrt haplotypes in southwestern uganda by high-resolution melt analysis.


BACKGROUND: Chloroquine (CQ) resistance is conferred by mutations in the Plasmodium falciparum CQ resistance transporter (pfcrt).

Auteurs: Kassaza K Long AC McDaniels JM Andre M Fredrickson W Nyehangane D Orikiriza P Operario DJ Bazira J Mwanga-Amumpaire JA Moore CC Guler JL Boum Y
Référence de l'article: Malaria journal 2021 Feb 25; 20(1); 114. doi: 10.1186/s12936-021-03657-7. Epub 2021 02 25
Chloroquine HRM Plasmodium falciparum Resistance Uganda pfcrt

Emergency department admission and hospitalization for COPD exacerbation and particulate matter short-term exposure in Brescia, a highly polluted town in northern Italy.


BACKGROUND: Short-term exposure to high Particulate Matter (PM) concentrations worsens several respiratory conditions.

Auteurs: Pini L Giordani J Gardini G Concoreggi C Pini A Perger E Vizzardi E Di Bona D Cappelli C Ciarfaglia M Tantucci C
Référence de l'article: Respiratory medicine 2021 Feb 16; 179(); 106334. doi: 10.1016/j.rmed.2021.106334. Epub 2021 02 16

Novel transdisciplinary methodology for cross-sectional analysis of snakebite epidemiology at national scale.


BACKGROUND: Worldwide, it is estimated that snakes bite 4.5-5.4 million people annually, 2.7 million of which are envenomed, and 81,000-138,000 die.

Auteurs: Alcoba G Ochoa C Babo Martins S Ruiz de Castañeda R Bolon I Wanda F Comte E Subedi M Shah B Ghimire A Gignoux E Luquero F Nkwescheu AS Sharma SK Chappuis F Ray N
Référence de l'article: PLoS neglected tropical diseases 2021 Feb 12; 15(2); e0009023. doi: 10.1371/journal.pntd.0009023. Epub 2021 02 12