Pour rechercher une publication scientifique, insérez vos mots-clés en anglais.

Immunogenicity and safety of fractional doses of 17D-213 yellow fever vaccine in HIV-infected people in Kenya (YEFE): a randomised, double-blind, non-inferiority substudy of a phase 4 trial.


BACKGROUND: Evidence indicates that fractional doses of yellow fever vaccine are safe and sufficiently immunogenic for use during yellow fever outbreaks.

Kimathi D Juan-Giner A Orindi B Grantz KH Bob NS Cheruiyot S Hamaluba M Kamau N Fall G Dia M Mosobo M Moki F Kiogora K Chirro O Thiong'o A Mwendwa J Guantai A Karanja HK Gitonga J Mugo D Ramko K Faye O Sanders EJ Grais RF Bejon P Warimwe GM
The Lancet. Infectious diseases 2023 Apr 28; . doi: 10.1016/S1473-3099(23)00114-7. Epub 2023 04 28

Comparative effectiveness of adding delamanid to a multidrug-resistant tuberculosis regimen comprised of three drugs likely to be effective.


Clarity about the role of delamanid in longer regimens for multidrug-resistant TB is needed after discordant Phase IIb and Phase III randomized controlled trial results.

Rodriguez CA Lodi S Horsburgh CR Mitnick CD Bastard M Huerga H Khan U Rich M Seung KJ Atwood S Manzur-Ul-Alam M Melikyan N Mpinda S Myint Z Naidoo Y Petrosyan O Salahuddin N Sarfaraz S Vilbrun SC Yae K Achar J Ahmed S Algozhina E Beauchamp J de Guadelupe Perea Moreno S Gulanbaeva M Gergedava M Indah Sari CY Hewison C Khan P Franke MF
PLOS global public health 2023 ; 3(4); . doi: 10.1371/journal.pgph.0000818. Epub 2023 04 28
Campbell JR Chan ED Anderson LF Bonnet M Brode SK Cegielski JP Guglielmetti L Singla R Fox GJ Skrahina A Rodrigues D Kuksa L Viiklepp P Menzies D
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2023 Apr 01; 27(4); . doi: 10.5588/ijtld.22.0678. Epub 2023 04 10

Mortality and Cause of Death in Children With Presumptive Disseminated Tuberculosis.


BACKGROUND AND OBJECTIVES: Children experience high tuberculosis (TB)-related mortality but causes of death among those with presumptive TB are poorly documented.

Bonnet M Nordholm AC Ssekyanzi B Byamukama O Orikiriza P Tusabe T Nyehangane D Taremwa IM Turyashemererwa E Wobudeya E Mwanga-Amumpaire J Marais BJ Nampijja D
Pediatrics 2023 Apr 01; 151(4); . doi: 10.1542/peds.2022-057912. Epub 2023 04 04

A prospective, multi-site, cohort study to estimate incidence of infection and disease due to Lassa fever virus in West African countries (the Enable Lassa research programme)-Study protocol.


BACKGROUND: Lassa fever (LF), a haemorrhagic illness caused by the Lassa fever virus (LASV), is endemic in West Africa and causes 5000 fatalities every year.

Penfold S Adegnika AA Asogun D Ayodeji O Azuogu BN Fischer WA Garry RF Grant DS Happi C N'Faly M Olayinka A Samuels R Sibley J Wohl DA Accrombessi M Adetifa I Annibaldis G Camacho A Dan-Nwafor C Deha ARE DeMarco J Duraffour S Goba A Grais R Günther S Honvou ÉJJP Ihekweazu C Jacobsen C Kanneh L Momoh M Ndiaye A Nsaibirni R Okogbenin S Ochu C Ogbaini E Logbo ÉPMA Sandi JD Schieffelin JS Verstraeten T Vielle NJ Yadouleton A Yovo EK
PloS one 2023 ; 18(3); . doi: 10.1371/journal.pone.0283643. Epub 2023 03 30

It takes more than a machine: A pilot feasibility study of point-of-care HIV-1 viral load testing at a lower-level health center in rural western Uganda.


Barriers continue to limit access to viral load (VL) monitoring across sub-Saharan Africa adversely impacting control of the HIV epidemic.

Boyce RM Ndizeye R Ngelese H Baguma E Shem B Rubinstein RJ Rockwell E Lotspeich SC Shook-Sa BE Ntaro M Nyehangane D Wohl DA Siedner MJ Mulogo EM
PLOS global public health 2023 ; 3(3); . doi: 10.1371/journal.pgph.0001678. Epub 2023 03 27

Assessment of the proportion of households with burn victims, associated risk factors and knowledge of burn injury prevention strategies in South Western Uganda. A population based cross sectional survey.


BACKGROUND: Burn injuries are a major cause of morbidity and mortality within Low- and Middle-income countries (LMICs). Most of these burn injuries occur at home with children most at risk.

Martin T Nanjebe D Atwine D
Burns : journal of the International Society for Burn Injuries 2023 Mar 24; . doi: 10.1016/j.burns.2023.03.016. Epub 2023 03 24
Adults Burn prevention Children Electricity protective Household burns Uganda

Acceptability of a new 4-in-1 Abacavir/Lamivudine/Lopinavir/Ritonavir paediatric fixed-dose combination: the caregiver-child dyads' perspective.


BACKGROUND: Worldwide, 1.7 million children younger than 15 years were living with HIV in 2021. Only 52% of them had access to antiretrovirals (ARVs). Lack of age-appropriate ARV formulations (i.e.

Rotsaert A Ogara C Mwanga-Amumpaire J Kekitiinwa AR Musiime V Najjingo E Kisitu GP Nazzinda R Nambi E Lee J Diallo M Kyomuhendo F Waweru M Andrieux-Meyer I Nöstlinger C
Therapeutic advances in infectious disease 2023 ; 10; . doi: 10.1177/20499361231159993. Epub 2023 03 21
HIV acceptability antiretroviral therapy fixed-dose combination paediatric ARV