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Safety of treatment regimens containing bedaquiline and delamanid in the endTB cohort.


RATIONALE: Safety of treatment for multidrug-resistant tuberculosis (MDR/RR-TB) can be an obstacle to treatment completion.

Hewison C Khan U Bastard M Lachenal N Coutisson S Osso E Ahmed S Khan P Franke MF Rich ML Varaine F Melikyan N Seung KJ Adenov M Adnan S Danielyan N Islam S Janmohamed A Karakozian H Kimenye MK Kirakosyan O Kholikulov B Krisnanda A Kumsa A Leblanc G Lecca L Nkuebe M Mamsa S Padayachee S Thit P Mitnick CD Huerga H
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022 Jan 13; doi: 10.1093/cid/ciac019. Epub 2022 01 13
MDR-TB QT prolongation adverse events linezolid new drugs

A cross-sectional analysis of mental health disorders in a mental health services-seeking population of children, adolescents, and young adults in the context of ongoing violence and displacement in northern Cameroon.


BACKGROUND: Displacement and conflict exposure are known risk factors for mental health conditions. Here, we examine the mental health of youth in a conflict-affected region of Cameroon.

Djatche JM Herrington OD Nzebou D Galusha D Boum Y Hassan S
Comprehensive psychiatry 2021 Dec 20; 113 152293. doi: 10.1016/j.comppsych.2021.152293. Epub 2021 12 20
Adolescents Anxiety Children Internally displaced persons Refugees Sub-Saharan Africa

Prenatal supplementation with multiple micronutrient supplements or medium-quantity lipid-based nutrient supplements has limited effects on child growth up to 24 months in rural Niger: a secondary analysis of a cluster randomized trial.


BACKGROUND: Prenatal multiple micronutrient supplementation (MMS) and lipid-based nutrient supplementation (LNS) can improve birth outcomes relative to iron-folic acid supplementation (IFA); however, effects on child postnatal growth r

Bliznashka L Sudfeld CR Garba S Guindo O Soumana I Adehossi I Langendorf C Grais RF Isanaka S
The American journal of clinical nutrition 2021 Dec 06; doi: 10.1093/ajcn/nqab404. Epub 2021 12 06
Niger child growth lipid-based nutrient supplements multiple micronutrient supplementation prenatal supplementation

Internalized stigma, depressive symptoms, and the modifying role of antiretroviral therapy: A cohort study in rural Uganda.


Depression affects over 40% of people with HIV (PHIV) in low- and middle-income countries, and over half of PHIV report HIV-related internalized stigma.

Bebell LM Kembabazi A Musinguzi N Martin JN Hunt PW Boum Y O'Laughlin KN Muzoora C Haberer JE Bwana MB Bangsberg DR Siedner MJ Tsai AC
SSM. Mental health 2021 Dec ; 1; . doi: 10.1016/j.ssmmh.2021.100034. Epub 2021 10 20
Antiretroviral therapy Depression Discrimination HIV Mental health Prejudice Stigma Sub-saharan africa Uganda

Cutaneous larva migrans in early infancy: A Ugandan case report.


Helminths are an important cause of worm infestation in low-income countries. The majority spread with soil to skin contact. In unusual patients presenting below 1 year, treatment can be challenging.

Muwanguzi E Kayiira M Kasozi D Kigozi E
Clinical case reports 2021 Nov ; 9(11); e05080. doi: 10.1002/ccr3.5080. Epub 2021 11 12
Uganda cutaneous larva migrans infancy topical albendazole

Prevalence of malaria in an area receiving seasonal malaria chemoprevention in Niger.


BACKGROUND: Malaria transmission is highly seasonal in Niger.

Coldiron ME Assao B Guindo O Sayinzoga-Makombe N Koscalova A Sterk E Quere M Ciglenecki I Mumina A Atti S Langendorf C Grais RF
Malaria journal 2021 Oct 24; 20(1); 419. doi: 10.1186/s12936-021-03953-2. Epub 2021 10 24
Malaria Niger Seasonal malaria chemoprevention